Serotonin Supplements – Brain Mood

Serotonin Supplements – Brain Mood Improvement

Improve Mood With Serotonin Supplements

The answer is yes. There is no boundary, previously in the Top 7 Nootropics article, I mentioned several nootropics that also enhance mood. In this article, the focus will be completely on supplements that improve overall mood instead of just focus, they are often referred to “serotonin supplements”.

  • What is the substance that impacts the human being’s mood in the brain?

Serotonin is involved as a chemical substance and is often named the “happy neurotransmitter”. Sufficient levels of serotonin in the brain allow you to feel a state of being calm and provides a sense of well-being.

On the contrary, an insufficient amount of this substance in your brain will cause mental diseases such as depression. Depending on the severity of depression, it can be a serious disease to battle with. One might be suffering from an acute form of depression, or the more severe – chronic depression.

The difference between these two forms of depression is that the acute form of depression is triggered by a horrifying event, such as loss – whether it is financial or losing a loved one. There are many reasons why one could be suffering from acute depression. The important thing to notice here is the difference that separates acute from chronic depression, the factor is the time it takes to heal.

People suffering from chronic depression are likely to battle this disease for longer. Millions of people suffer from some kind of depression and they are taking treatment medication. Some of the most prescribed medications include Monoamine Oxidase Inhibitors (MAOI) and Selective Serotonin Reuptake Inhibitors (SSRIs).

Both of the medication classifications above work by influencing the inner-brain Dopamine and Serotonin levels. No single drug exists that will treat all of the patients the same since every form of depression is very unique.

Therefore, not all medications or supplements might work for you. Taken, for example, the extract 5-HTP from Griffonia Simplicifolia extract – 5-HTP is the main source of serotonin supplements, can be equally effective in reducing depression symptoms as some prescribed medication.

If you are already taking prescription medication, first consult with your doctor and do not take more supplements that might increase your serotonin levels.

Another hormone that plays an important role as a neurotransmitter is Oxytocin. This hormone is referred to as the “love hormone”. It contributes to couples bonding and is vastly synthesized in our body when we hug or interact with our loved ones. It stimulates a sense of pleasant feeling and calmness. Anyway, I should not deviate from the topic this much.

The supplements available on the market today are mixes of various substances. They come as a single substance in rare cases, except vitamins or minerals. It is very common for vitamin supplements to include a standalone substance such as Vitamin C, Vitamin D, etc.

  • Is it possible to increase serotonin levels without serotonin supplements?

Well, since supplements are an addition to your diet it is possible to alter your diet and achieve results similar to those with supplements. Using serotonin supplements is a shortcut with the correct substances because not always one can follow a specific diet.

The food you can eat and balance your serotonin levels are the following:

  • Lean cuts of meat
  • Whole grain foods (usually rich in vitamin B6)
  • Salmon and tuna
  • Majority of dairy products (rich in vitamin D)

Having a healthy lifestyle also requires daily physical activity. Health professionals recommend at least 45 minutes of physical activity per day. This will also balance mood and lessen depression in any form.

The following supplements are picked based on the substances they contain, user review, and rating.

The Brain Supplements for mood or “Serotonin supplements” we will be reviewing are:

  • Pure Balance Serotonin Supplement
  • Clarity by Neovicta – Improves mood significantly and elevates performance with no crashes or jitter caused after.
  • HCF Happy Calm Focused Brain Supplement
  • Brain Mood from Douglas Laboratories – Promotes good mood and sense of well-being
  • Onnit New Mood – Daily Stress and Mood Support Supplement

You can review each supplement with detailed information and supplement facts included.

Brain Mood by Douglas Laboratories – Improves Mood and Provides Sense of Well-Being

This synergistic blend of multiple ingredients is manufactured by Douglas Laboratories and mainly promotes good feelings, sense of well-being, etc. Serotonin and its precursor amino acid – tryptophan, allow the brain to restore and maintain mood at a healthy level. Brain Mood’s formula has all ingredients that the human brain requires for serotonin production. This helps significantly with maintaining brain symmetry. Because of stimulating serotonin production these products are often referred to as serotonin supplements.Brain Mood by Douglas Laboratories

Physicians recommend for adults to take capsules in dosages of 3 capsules per day.

Note: This product contains no yeast, wheat, soy protein, dairy products, and is gluten-free. This product is also not designed to cure a disease, it is manufactured as a supplement to improve current health status.


Thiamine is another name for vitamin B1, deficiency of this vitamin can prove fatal. In cases with less severity, signs include irritability, confusion, and loss of orientation. It was first made in 1936 and is on the list of most essential medicine proven to be effective and very safe in the health system.

Folic Acid

Folic acid or vitamin B9 is one of the vitamins in the B vitamin group. Deficiency of folic acid is manifested by fewer large red blood cells.  The symptoms often include feeling tired, shortness of breath, fatigue, in some cases it might even lead to anemia. This substance is also known as folate.

Pantothenic Acid

Vitamin B5 or pantothenic acid is a water-soluble vitamin. You can often find vitamin B5 in manufactured and ready to eat foods such as cereal, energy bars or dried foods.

The adequate intake for an adult man/woman is about 5 mg per day. Pregnant women should consume 1-2mg per day more than normal, either from a diet or supplement.


You can see the full supplement facts in the table below.

Thiamine(as Thiamine HCL)15mg
Folic Acid300mcg
Vitamin B12
(as cyanocobalmin)
Pantothenic Acid
(as Calcium Pantothenate)
5-Hydroxytryptophan 100mg
St.John's Wort Extract
(flowers and tops)(standardized to contain 0.3% hypercin)

Onnit New Mood – Daily Stress and Mood Support Supplement

Onnit New Mood is a great supplement to get rid of occasional daily stress. It can be referred to as the serotonin supplement or serotonin supplement regulation. Both of the building blocks of serotonin – L-tryptophan and 5-HTP in addition to Vitamin B6 which is a converting catalyst help regulate serotonin in the body.Onnit-New-Mood

The most important substance in this mix is serotonin, but you cannot take serotonin alone and expect results. This is because of two reasons, serotonin alone cannot cross the blood-brain barrier and because serotonin needs to be produced by the body so you could have benefits.

This problem is solved by supplying your body with the building blocks of serotonin. The building blocks include Tryptophan and 5-HTP as mentioned above.

  • What happens when you take Onnit New Mood?

First, the production begins with L-Tryptophan – the common amino acid and develops into 5-HTP which is the precursor of the essential neurotransmitter 5-HT.

New Mood from Onnit provides both these substances with Vitamin B6 included which assists in the body’s serotonin generating process.

These substances are included to improve your mood however they are not the only substances in this supplement mix. The full list of ingredients includes:

  • Vitamin B3 (Niacin)

Vitamin B3 or niacin is important for health in general. It lowers the level of cholesterol in the blood and boosts good levels of HDL cholesterol. Niacin is used as a cholesterol treatment but the high dosages used might cause gastrointestinal and other problems.

Mainly, vitamin B3 is good for the cardiovascular system and you can get enough of it if you follow a healthy diet or by consuming additional supplements.

  • Magnesium

Magnesium is responsible for the functioning of many vital enzymes. Good magnesium diet must consist of sunflower seeds, almonds, and shrimp. If, for some reasons you are not able to follow a diet, you can consume it from additional supplements.

  • Tryptophan (L-Tryptophan)

This is an essential amino acid which the body cannot produce itself. The only source is food or supplements, tryptophan is a protein building block which deficiency can cause serious symptoms. They include sleep apnea, depression, facial pain, and anxiety.

After consuming food that contains L-tryptophan, the human body will convert it into 5-HTP (5-hydroxytryptophan). The 5-HTP then synthesizes into serotonin – the key element for mood.

  • Vitamin B6

The metabolically active form of this vitamin contributes to many areas of macronutrient metabolism, hemoglobin, histamine and neurotransmitter synthesis. The most common form of vitamin B6 is Pyridoxine or PN, the metabolically active substance is PLP or Pyridoxal 5 phosphate.

  • 5-HTP

As mentioned above in the paragraph, 5-HTP is a precursor to serotonin and the body can synthesize it on its own from other food substances. It plays an important role in mood regulation.

You can consume New Mood in the morning to improve your mood during your day and before going to bed to enhance your sleep. It can help you with anxiety before a public speech, a final exam or a party. New Mood does not form a dependency or a habit, it is completely safe to use.


You can see the full supplement facts in the table below.

Niacin (as Inositol Hexanicotinate)30mg
Vitamin B620mg
Magnesium (as Magnesium Bisglycinate Chelate)40mg
Onnit Tranquility Blend
-Valerian (root) Extract
-Chamomile (flower) Extract
-Lemon Blam (aerial parts) Extract
-Jujube (seed) Extract
5-HTP 150mg
Inositol (as Inositol Hexanicotinate)12mg


Total Focus Formula For Added Attention Boost Mood And Anti-Stress

Are you a starter when it comes to nootropics, and is scared about side effects, well Total focus is just the right nootropic for you.
Total focus has no side effects when it comes to it because it contains a power-packed organic formulation of strong herbs and nootropics.
Total focus in itself contains the following ingredients:

  • Clinically Proven Organic Ashwagandha Extract
  • Organic Panax Ginseng Extract
  • Organic Ginkgo Biloba Extract
  • Organic Chaga Mushroom Extract
  • Vitamin B-5


Why total focus?

Total Focus is created by the company Gaia Sciences which mostly creates nootropics made out of organic materials, so for this nootropic, they pulled many of the most renowned natural compounds that have been known, and used for mental energy and improved brain performance.
Total focus is a 100% safe and effective while being natural performance booster and cognitive enhancer.
Total focus has a wide range of ingredients, which on their own have outstanding effects, but when combined they create an even more impressive result.
This nootropic is considered as one of the best in its price range and it’s many outstanding effects, like:

  • Cognitive enhancement
  • Metabolic support
  • Anti-aging support
  • Energy and Sports performance support
  • Muscle recovery
  • Alertness, memory
  • Improvement of oxygen usage

And a lot more that comes from its unique ingredients.

Usage of Total focus, and recommendations.
The daily recommendation for taking Total focus is one or two capsules daily, preferably with a meal for better results, and better absorption.
A tip from us would be taking 1 capsule after dinner since that makes the active ingredients available during the regenerative phase of sleep. Have in mind changing your diet, for better results, meaning avoids gluten, processed foods, and everything with artificial ingredients. Total focus is non-GMO, does not contain artificial colors, flavors, sweeteners, no preservatives, sugar, starch, milk, lactose, soy, gluten, wheat, yeast, fish, and is sodium free.


You can see the full supplement facts in the table below.

Organic KSM-66 Ashwagandha Full-Spectrum
Organic Panax Ginseng (S.E. 3% Ginsenoside)200mg
Organic Ginkgo Biloba150mg
Ginkgo Biloba (24% Extract)36mg
Organic Chaga mushroom Extract100mg
Bacopa Monnieri (20% Bacosides)100mg
Phosphatidylserine (20%)100mg
Vitamin B-5 (D-calcium pantothenate)20mg
Black Pepper Extract5mg


HCF Happy – Calm Focused Brain Supplement

HCF Happy Brain supplement is fully packed with vitamins mostly, some essential minerals and amino acids.

Minerals and vitamins are known nutrients for essential functions of the brain and body in general. They are mostly consumed through everyday food. You need to be very selective and careful about your meals in order to contribute with the right amount of needed minerals, vitamins, and amino acids. Otherwise, it is good to consider taking a supplement to cover the deficiency and stay healthy.

Proper nutrition or a supplement will grant you better brain functioning such as memory, focus and the most important one in this topic – mood improvement.

HCF Happy Brain supplement strengthens neural pathways, contributes to hormone balance, helps you be energized and strong, and supports learning capabilities improvement.

Looking at the supplement facts, it looks quite promising. There are no synthesized substances at all, the ingredients are natural.


The full supplement facts list:

  • Vitamin A
  • Vitamin E
  • Vitamin B1
  • Vitamin B2
  • Vitamin B3
  • Vitamin B6
  • Folic Acid
  • Vitamin B12
  • Vitamin B5
  • Calcium
  • Iron
  • Magnesium
  • Zinc
  • Chromium


You can see the full supplement facts in the table below.

VItamin A (as beta carotene)1000 IU
Vitamin E (as d-alpha-tocopherol succinate)1.5 IU
Vitamin B1 (as thiamine HCL)3mg
Vitamin B2 (as riboflavin)3mg
Vitamin B3 (as niacin & niacinamide)6mg
Vitamin B6 (as pyridoxine HCL)3mg
Magnesium (as magnesium oxide)30mg
Folic Acid150mcg
Iron (as ferrous fumarate)3mg
Vitamin B12 (as methylcobalamin)150mcg
Calcium (as calcium citrate)30mg
Vitamin B5( as d-calcium pantothenate)3mg
Zinc (as zinc citrate & zinc picolinate)6mg
Chromium (as chromium polynicotinate)225mcg

Pure Balance Serotonin – Balancing Mood and Cortisol Level Control

Unlike most of the supplements, this Pure Balance Serotonin has fewer substances on the supplement fact list. The natural herbs contained in this supplement will help you improve your mood, including appetite suppression, stress and sleep management, weight control, acute stress situations relief.

  • Pure Balance Serotonin Supplement provides key herbs to the body which are used to produce serotonin. This is a natural way of managing serotonin levels without any synthesized drugs.
  • The 5-HTP, Relora, Rhodiola, and Vitamin D3 are clinically proven to help on this matter.
  • Both acute and chronic stress situations can manifest with insomnia during nights, this supplement will help you improve your sleep significantly.

One of the fewer supplements that contain Relora. Relora is a combined product of two Chinese tree barks used to suppress stress and stressful situations. This can be reviewed as a single product but in this case, we can review it in order to examine Pure Balance Serotonin supplement facts more thoroughly.

Benefits of Relora

  • Balances adrenal function
  • Builds up your tolerance to occasional stress
  • Promotes calmness  without causing drowsiness
  • Deals with forms of insomnia/ improve sleep

Stress and HPA Axis – Relora Balancing

When you are feeling stressed, your body goes through something called “fight or flight” as you might have heard before. During this defensive response, the body secretes increased amounts of cortisol and adrenaline.

Stress hormones are released into the body by the HPA Axis, an abbreviation for Hypothalamus, Pituitary gland, and Adrenal (stress) glands. When stress levels are high, the balance in this system is out of control.

This product contains 90 servings per container, which is very unusual for other supplements.

Rhodiola Rosea

Rhodiola Rosea is another natural extract that fights symptoms of depression. It is considered as an adaptogenic herb, which means it builds up resistance to stress without altering normal biological functions in the body.


This substance is also known under the name of Suntheanine. It has two main sources from nature which it can be derived from – Tea and the edible mushroom Boletus Badius. Tea is native to eastern Asia and grows up to 9 meters in height.

The Boletus Badius mushroom is often commonly found in late summer and autumn in the United States with a reddish color.

It was discovered as a substance in the second most consumed beverage in the world – Tea and was approved in Japan for usage in all foods including soft drinks and chocolate.

L-theanine helps with relieving stress and has a relaxing effect with no drowsiness. It may also improve immunologic attributes and may also have an effect on the cardiovascular system. This means the substance plays a preventative role in cancer. There is very little clinical evidence to confirm the importance of preventing cancer of L-theanine.

The dosage usually varies in between 200 to 250mg.

So far there are no serious contraindications established and it is considered fairly safe.


You can see the full supplement facts in the table below.

Vitamin D3 (as cholecalciferol)267 IU
5-HTP (L-5 hydroxytryptophan)
(from Griffonia simplicifolia seed)
33 mg
L-Theanine67 mg
Relora proprietary blend
(Magnolia standardized bark extract)
(Phellodendron standardized bark extract)
250 mg
Rhodiola extract (root)
(Standardized for 5% rosavins [6mg])
120 mg



Final Words on Serotonin Supplements

It might be a bit healthier to consume the substances above from a certain diet, but when you cannot allow yourself to follow the one you should consider taking supplements.

Mood problems such as depression and bipolar disorder are a serious matter and should not be laughed about. While serotonin supplements might not be able to treat severe cases of mood disorder they will certainly be able to help and help suppress mild cases of anxiety and mood disorders.

Antidepressants or anxiety medication very often stop working or have very unpleasant side effects. The annual cost of treatment with this kind of diseases costs about $52 billion in the United States alone.

People are more concerned with finding a mood supplement that would help as an alternative to drugs. Changes, for mood improvement, could also mean changes in lifestyle, diet, and exercise. Some of the substances your supplement will provide, your body could make it on its own while doing exercises which results in lifting self-esteem and satisfaction.

You should use supplements as an addition to your food in order to complete it

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